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Healing from the Inside Out: Regenerative Medicine for Foot and Ankle Pain with Amnio Injections

  • heelandtoepodiatry
  • 2 days ago
  • 4 min read

By R. Scott Johnston, DPM


Regenerative Medicine can Help
Regenerative Medicine Can Help

Living with chronic foot or ankle pain can affect every step you take. Whether it’s plantar fasciitis, tendon injuries, or arthritis, discomfort in the lower extremities can limit your ability to walk, exercise, or simply enjoy your daily routine. Traditionally, patients have turned to pain medications, steroid injections, or even surgery when conservative care fails. Today, however, there’s an exciting alternative: regenerative medicine using amniotic membrane injections (also called amnio injections).


As a podiatrist specializing in foot and ankle care, I’ve seen how regenerative treatments can help patients recover faster, reduce pain, and avoid surgery. Let’s take a closer look at how this innovative therapy works.


What Are Amnio Injections?

Amnio injections are a type of regenerative medicine treatment for foot and ankle pain. They use amniotic tissue—naturally rich in growth factors, proteins, and cytokines—that helps the body repair damaged tissue. Unlike corticosteroid injections, which temporarily reduce inflammation, amniotic injections stimulate true healing on a cellular level.

Amniotic tissue is ethically sourced, carefully processed, and has been used safely in multiple areas of medicine, including wound care, eye surgery, and now podiatry.



Conditions Treated with Regenerative Medicine for Foot and Ankle Pain

Amnio injections may benefit patients struggling with:

  • Plantar fasciitis and heel pain – A leading cause of discomfort, especially in active adults.

  • Achilles tendinitis – Chronic inflammation or microtears in the tendon.

  • Ligament injuries and ankle sprains – For patients with lingering pain or instability.

  • Arthritis in the foot and ankle joints – Especially when traditional treatments no longer bring relief.

  • Non-healing soft tissue injuries – Conditions resistant to physical therapy or standard care.


Key Benefits of Amniotic Injections

Patients are turning to regenerative medicine because it offers unique advantages:

  1. Promotes true healing rather than masking pain.

  2. Reduces inflammation and stiffness for better mobility.

  3. Minimally invasive in-office procedure with little downtime.

  4. Alternative to steroids or surgery, offering a natural solution.

  5. Improved function and quality of life so patients can get back to the activities they love.


What to Expect During Treatment

The procedure is quick and performed in-office. Using ultrasound guidance, the injection is placed directly at the site of injury or inflammation. Most patients report only mild discomfort, and recovery time is minimal. Improvements typically build over several weeks, with many patients experiencing long-lasting relief from chronic foot or ankle pain.


Is Regenerative Medicine Right for You?

If you’re searching for non-surgical treatments for foot and ankle pain, regenerative medicine may be the next step. Whether you’re dealing with heel pain, Achilles issues, or arthritis, amnio injections could help your body heal naturally.

At my office, I evaluate each patient individually to determine whether regenerative therapy is the best option. If conservative care hasn’t worked and you’d like to avoid surgery, this innovative treatment may be the solution.


Average Cost of Treatment at Heel and Toe Podiatry:

  • Per injection: $850

  • Complete treatment plan: $850 – $5,000 (depending on the number of sessions required)


Does Insurance Cover Amniotic Fluid Therapy?

  • Most insurance providers do not cover regenerative treatments, as they are considered elective procedures.

  • Some flexible spending accounts (FSA) or health savings accounts (HSA) may be used to cover part of the cost.

  • We offer flexible payment plans and financing options to help make this innovative treatment more accessible.


Recovery Process and Expected Results

The recovery process after Amniotic Fluid Therapy is typically quick and minimally disruptive, allowing patients to return to their daily activities with little to no downtime. Since this treatment stimulates natural healing, results develop gradually over time as the body repairs and regenerates damaged tissues.


1. Immediate Post-Treatment Phase (0-2 Weeks)

  • Most patients experience mild soreness or swelling at the injection site, which usually resolves within a few days.

  • Ice packs and over-the-counter pain relievers (avoiding NSAIDs like ibuprofen, which may slow healing) can be used for discomfort.

  • Patients can resume daily activities within 24-48 hours, but high-impact activities should be avoided initially.

2. Early Healing Phase (3-6 Weeks)

  • The growth factors and cytokines in amniotic fluid begin stimulating tissue regeneration and reducing inflammation.

  • Patients may notice gradual pain relief and increased mobility.

  • Physical therapy or light stretching may be introduced to enhance recovery.

3. Full Recovery and Maximum Results (2-6 Months)

  • The full regenerative effects of Amniotic Fluid Therapy become evident as damaged tissues rebuild and pain continues to decrease.

  • Most patients experience long-term relief from chronic foot and ankle pain.

  • For severe injuries or degenerative conditions, additional treatments may be recommended to optimize healing.


How Long Do Results Last?

  • The effects of Amniotic Fluid Therapy can last several months to years, depending on the severity of the condition and the patient’s lifestyle.

  • Unlike cortisone injections, which only provide temporary symptom relief, amniotic fluid actively repairs damaged tissues, offering longer-lasting benefits.


Dr. Johnston, DPM Helping patients find lasting relief with regenerative medicine for foot and ankle conditions.


Heel and Toe Podiatry, Perrysburg Podiatrist, Perrysburg Foot Doctor, Perrysburg Toe Doctor, Fall Footwear, Scott Johnston, podiatrist


R. Scott Johnston, DPM

1021 Sandusky St.

Suite A

Perrysburg, OH


419-474-7700


Office Hours:

  Tuesday 8:30 am - 4:30 pm

  Wednesday 8:30 am - 12 pm

  Thursday: 8:30am - 4:30 pm

  Friday: 8am - 1pm


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